Association between anti-Ro 60kDa (SS-A) autoantibodies and hypocomplementemia in systemic lupus erythematosus patients from Algiers prefectures
نویسندگان
چکیده
منابع مشابه
Production of anti-Ro/SS-A and anti-La/SS-B autoantibodies is closely coordinated in systemic lupus erythematosus and independent of anti-dsDNA production.
Autoimmune diseases such as Sjögren's Syndrome and systemic lupus erythematosus (SLE) are characterized by serum autoantibodies against protein components of small cytoplasmic ribonucleoproteins (scRNPs). The origin and regulation of these anti-Ro/SS-A and anti-La/SS-B antibodies is not well understood. Regular co-occurrence of these two autoantibodies in humans together with murine studies on ...
متن کاملRare Association between Kikuchi's Disease and Systemic Lupus Erythematosus
Histiocytic necrotizing lymphadenitis or Kikuchi's disease is a rare, benign condition of unknown etiology, which is usually characterized by cervical lymphadenopathy and fever. This disease is rarely associated with systemic lupus erythematosus. Here we describe, for the first time in Iran, a patient who developed systemic lupus erythematosus about 3 years after the initial diagnosis of Kikuch...
متن کاملANTINEUTROPHIL CY TOPLASMIC AUTOANTIBODIES IN SYSTEMIC LUPUS ERYTHEMATOSUS
Antineutrophil cytoplasmic autoantibodies (ANCA) were first described in patients with necrotizing glomerulonephritis. The original observation passed unnoticed until an association was made between ANCA and active Wegener's granulomatosis. Since then, tremendous progress has been made in elucidating the association between ANCA subtypes and clinicopathologic syndromes, and the potential p...
متن کاملAnti-Ro/SS-A and anti-La/SS-B antibodies associated with cardiac involvement in childhood systemic lupus erythematosus.
OBJECTIVES To determine the frequency and type of cardiac manifestations in children with systemic lupus erythematosus (SLE) and investigate whether cardiac involvement of SLE in children was associated with any autoantibody pattern. METHODS Retrospective analysis of the medical records of all children with SLE (31 patients) seen between January 1984 and January 1994 by the paediatric rheumat...
متن کاملFluctuation of anti-Ro/SS-A antibody levels in patients with systemic lupus erythematosus and Sjögren's syndrome: a prospective study.
OBJECTIVE To determine whether the titers of anti-Ro/SS-A (Ro) antibodies fluctuate during the course of SLE and Sjögren's syndrome (SS) in parallel with disease activity, and if such fluctuations could be used to predict disease flares. We also evaluated whether the anti-Ro profile (anti-Ro 52, anti-Ro 60) changes over time, since such information could provide new insights into the induction ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Egyptian Rheumatologist
سال: 2016
ISSN: 1110-1164
DOI: 10.1016/j.ejr.2016.01.002